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5 edition of Molecular control mechanisms in striated muscle contraction found in the catalog.

Molecular control mechanisms in striated muscle contraction

Molecular control mechanisms in striated muscle contraction

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  • 5 Currently reading

Published by Kluwer Academic Publishers in Dordrecht, Boston .
Written in English

    Subjects:
  • Muscle contraction -- Regulation,
  • Muscles -- Molecular aspects

  • Edition Notes

    Includes bibliographical references.

    Statementedited by R. John Solaro and Richard L. Moss.
    SeriesAdvances in muscle research -- v. 1
    ContributionsSolaro, R. John., Moss, Richard L. Ph.D.
    Classifications
    LC ClassificationsQP321 .M763 2002
    The Physical Object
    Paginationxi, 468 p. :
    Number of Pages468
    ID Numbers
    Open LibraryOL19288582M
    ISBN 101402007345
    LC Control Number2002031646

    The Molecular Mechanism of Muscle Contraction. Myosin from muscle (myosin II) consists of two long polypeptide chains (heavy chains) combined with four light chains. In cross-striated muscle, the tails of the molecules pack together to form the thick filaments, while the crossbridges that are ATPases point away from the thick filaments and. Myofibrillogenesis in striated muscle cells requires a precise ordered pathway to assemble different proteins into a linear array of sarcomeres. The sarcomere relies on interdigitated thick and thin filaments to ensure muscle contraction, as well as properly folded and catalytically active myosin head.

    Recent years have witnessed an explosion of knowledge lea- ding to a molecular understanding of the mechanisms of ac- tion of calcium on excitation and contraction coupling and its role in the regulation of contractility. This book highlights the most recent progress . Download Citation | The Frank -Starling Relationship: Cellular and Molecular Mechanisms | It is probably not an exaggeration to suggest that the modern era of cardiovascular research began with.

    Start studying Molecular mechanisms of muscle contraction. Learn vocabulary, terms, and more with flashcards, games, and other study tools. The whole process is called the mechanism of muscle contraction and it can be summarized in three steps: (1) A message travels from the nervous system to the muscular system, triggering chemical reactions. (2) The chemical reactions lead to the muscle fibers reorganizing themselves in a way that shortens the muscle--that’s the contraction.


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Molecular control mechanisms in striated muscle contraction Download PDF EPUB FB2

About this book Introduction Molecular Control Mechanisms in Striated Muscle Contraction addresses the molecular mechanisms by which contraction of heart and skeletal muscles is regulated, as well as the modulation of these mechanisms by important (patho)physiological variables such as ionic composition of the myoplasm and phosphorylations of contractile and regulatory proteins.

Molecular Control Mechanisms in Striated Muscle Contraction addresses the molecular mechanisms by which contraction of heart and skeletal muscles is regulated, as well as the modulation of these mechanisms by important (patho)physiological variables such as ionic composition of the myoplasm and phosphorylations of contractile and regulatory proteins.

"Molecular Control Mechanisms in Striated Muscle Contraction addresses the molecular mechanisms by which contraction of heart and skeletal muscles is regulated, as well as the modulation of these mechanisms by important (patho)physiological variables such as ionic composition of the myoplasm and phosphorylations of contractile and regulatory proteins.".

Striated or skeletal muscle is both highly specialised and very common in the vertebrate body. In this book, Professor Perry discusses and evaluates the great strides that have been taken recently to further our understanding of the molecular mechanisms and regulatory processes in both normal and diseased muscle.

In the field of the molecular mechanism of contraction in striated muscle, the stepwise progress was achieved by three great investigators in \'s and \'s. In the early \'s, Albert Szent-Gyorgyi and his associates showed biochemically that muscle contraction is essentially an interaction between actin and myosin coupled with ATP hydrolysis.

The book focuses on the molecular and cellular facets of skeletal muscle function. The selection first offers information on the mechanical properties of cross-bridges and their relation to muscle contraction; molecular basis of functional specialization in muscle as induced by innervation; and electrical properties of crustacean muscle membranes.

Molecular control mechanisms in muscle contraction. A Weber, and ; J M Murray; A Weber. Search for more papers by this author Molecular mechanisms in muscular contraction.

Trends in Neurosciences, Vol. 6 The mechanism for vertebrate striated muscle contraction. Circulation Research, Vol. 42, No. Regulatory Mechanisms of Striated Muscle Contraction.

Editors (view affiliations) Setsuro Ebashi Citations; 39k Downloads; Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume ) Log in to check access. Buy eBook.

USD Molecular Pathogenic Mechanisms of Cardiomyopathies Caused by Mutations in. Striated muscles and the huxley-hanson model. Striated muscles have a relatively simple morphology with no bends or curvatures but exhibit large complexity in the organization of their main molecular constituents: actin, myosin, titin, and numerous minor components, all of which form the contractile sarcomer cell schematized in Figure Figure1A 1A in the contracted state.

Skeletal muscle innervation is a multi-step process leading to the neuromuscular junction (NMJ) apparatus formation. The transmission of the signal from nerve to muscle occurs at the NMJ level.

The molecular mechanism that orchestrates the organization and functioning of synapses is highly complex, and it has not been completely elucidated so far. When the sarcomeres within a muscle cell contract, the muscle itself contracts and shortens.

In the accompanying animation, we examine the mechanism by which a sarcomere shortens during contraction. CONCLUSION. A muscle contraction can be explained by the cycle of molecular events that take place between actin and myosin filaments.

Regulation of contraction in vertebrate striated muscle is linked to the thin filament. The initial and critical step in activation is the binding of regulatory Ca 2+ to specific sites in troponin.

Molecular Control Mechanisms in Striated Muscle Contraction. The reader is directed to the following books for recent summaries of the broad Trafford A.W., Eisner D.A. () Excitation-Contraction Coupling in Cardiac Muscle. In: Solaro R.J., Moss R.L.

(eds) Molecular Control Mechanisms in Striated Muscle Contraction. Advances in Muscle. González A., Ríos E. () Excitation-Contraction Coupling in Skeletal Muscle. In: Solaro R.J., Moss R.L. (eds) Molecular Control Mechanisms in Striated Muscle Contraction.

Advances in Muscle. The ability of a muscle to generate active force and shorten resides within the cellular machinery of the individual muscle fibers. It is the goal of this chapter to describe the molecular mechanisms within a muscle fiber that control its ability to contract and relax, and the main regulatory systems that govern these functions.

Many color figures illustrate the three-dimensional structures of the proteins involved in the muscle functions. The book will help readers understand characteristic features of the regulatory mechanisms of striated muscle contraction and their disorders at the molecular level.

Application of Muscle/Nerve Stimulation in Health and Disease Series: Advances in Muscle Research, Vol. 4 Vrbová, Gerta, Hudlicka, Olga, Schaefer Centofanti, Kristin The molecular events of muscle fiber shortening occur within the fiber’s sarcomeres (see Figure 3).The contraction of a striated muscle fiber occurs as the sarcomeres, linearly arranged within myofibrils, shorten as myosin heads pull on the actin filaments.

Molecular mechansim of muscle contraction: Actin filaments slide inward among the myosin filaments due to forces generated by interaction of the cross bridges from the myosin filaments with the actin filaments. Author(s): Solaro,R John; Moss,Richard L(Richard Lee) Title(s): Molecular control mechanisms in striated muscle contraction/ edited by R.

John Solaro and Richard L. Moss. Country of Publication: Netherlands Publisher: Dordrecht ; Boston: Kluwer Academic Publishers, c. A muscle contraction is an increase in the tension or a decrease in the length of a muscle. Muscle tension is the force exerted by the muscle on a bone or other object.

A muscle contraction is isometric if muscle tension changes, but muscle length remains the same. An example of isometric muscle contraction is holding a book in the same position.Ca 2+-DEPENDENT CONTRACTION OF SMOOTH MUSCLE. Contraction of smooth muscle is initiated by a Ca 2+-mediated change in the thick filaments, whereas in striated muscle Ca 2+ mediates contraction by changes in the thin filaments.

In response to specific stimuli in smooth muscle, the intracellular concentration of Ca 2+ increases, and this activator Ca 2+ combines with the acidic .Adom González, Eduardo Ríos, Excitation-Contraction Coupling in Skeletal Muscle, Molecular Control Mechanisms in Striated Muscle Contraction, /_1, (), ().

Crossref Michele Chiesi, Cross-linking agents induce rapid calcium release from skeletal muscle sarcoplasmic reticulum, Biochemistry, /bia,